Mesangial proliferative glomerulonephritis and nephrotic syndrome with hepatitis A virus infection.

A 7-year-old boy was admitted with seven day history of fever, anorexia, abdominal discomfort and vomiting. On examination, the child was febrile (10FF) with a respiratory rate of 34/min and a normal blood pressure. Icterus was present. He had epigastric and right upper quadrant tenderness. There was no hepatomegaly. Serum bilirubin was 2.3 mg/dl with a direct fraction of 0.4 mg/dl. Urine for bile pigments, salts and urobilinogen was positive. Further serial laboratory data is shown in Table I. Viral serology demonstrated the presence of